NCBI C Toolkit Changes Since Version 2.2.9 ------------------------------------------ 1. BlastPGP - added code to spread out gap costs when extracting data from the sequence alignment to build PSSM - changed handling of all-zero columns of residue frequencies to use the underlying scoring matrix frequency ratios rather than scoring matrix's scores - disallowed an ungapped search if more than one iteration is specified - added input/output of residue frequencies as scoremat objects 2. Score-mat objects - changed ASN.1 specification for Score-Matrix to use floating point instead of fixed point for residue frequencies and weights - added a new 'formatrpsdb' application; given a collection of Score-mat ASN.1 files, this application creates a database suitable for use with RPSBLAST 3. General changes: - consolidated formatting code - removed fmerge.c - small fixes to sum statistics code - better error handling - fixed masking of translated queries - fixed several readdb threading bugs